Coleus is a plant that has been used since ancient times in Ayurvedic and Hindu traditional medicine. The root portion has been traditionally used to treat colic, congestive heart failure, convulsions, eczema, hypertension, insomnia, painful urination and respiratory disorders.
Use of Coleus also provides therapeutic benefit in angina, asthma, psoriasis and prevention of cancer metastases.
Antioxidant: Forskolin shows high amount of polyphenols and higher antioxidant activity. Leaf extract of this plant exhibited significantly high amount of total polyphenols, flavonols and flavones and high antioxidant activity. Coleus can be used as an important source of phenolic compounds with significantly high antioxidant activity (Rasineni et al., 2008).
Under normal circumstances, cAMP forms by adenylate cyclase activation due to hormonal stimulation at the cell receptor site. However, forskolin seems to bypass this reaction and allows for an increase in intracellular cAMP to occur.
Well, there are several benefits of this to athletes including relaxation of the arteries and smooth muscles, lowering blood pressure, enhanced insulin secretion (which can help drive carbohydrates and protein into muscle cells for energy and recovery), increased thyroid hormone function (which can help enhance metabolic rate), and significantly increase lipolysis (fat burning). Forskolin also seems to benefit other cellular enzymes as well.
The breakdown of fat for fuel (lipolysis) is actually regulated by cAMP. Forskolin has been shown to not only enhance lipolysis but it may also inhibit fat storage from occurring. This is very good news for individuals trying to lose body fat and get lean.
Another way that forskolin may allow for fat loss to occur is by stimulating thyroid hormone production and release. Thyroid hormone controls metabolism and can enhance metabolic rate, which may translate into more fat loss.
Like a lot of research on forskolin, the research linking it with a treatment for Alzheimer’s is in its infancy. However, a promising study published in the Journal of Neuropathology and Experimental Neurology performed on rats in July 2016 found administration of forskolin greatly decreased many negative physical components caused by Alzheimer’s disease, including plaque in various areas of the brain and reduced inflammatory activity. This is incredibly encouraging in the area of natural Alzheimer’s treatment.
A 2014 study on glycemia and oxidative stress in rats looked at forskolin’s effectiveness on the two conditions. The study, published in the International Journal of Medical Sciences, indicated that regular administration of forskolin (over the course of eight weeks) decreased fasting blood glucose levels. While this preliminary study shows that this supplement may help diabetic and prediabetic patients, more research must be done in order to prove its level of efficacy.
Coleus also works well in treating asthma, cancer, cardiopathy, congestive heart failure, convulsions, cramp, depression, dermatosis, dyspepsia, dysuria, eczema, glaucoma, high blood pressure, hypothyroidism, infertility, insomnia, ischemia, myocardosis, obesity, psoriasis, respirosis, thrombosis and water retention (Duke et al., 2002).
Varion® offers 4 premium Coleus Products:
Coleus Extract 10, 20, 40% is a mostly soluble, yellow red powder that is Kosher and food grade certified and is produced in a BRC certified facility.
Coleus Extract – 95% (Cosmetics Application) is a mostly soluble, fine creamish powder that is certified Kosher and food-grade certified and is produced in a BRC certified facility.
For 16 years Varion® LifeSciences Pvt Ltd has been supplying customers with the finest nutraceutical ingredients produced at our own facilities in India. Our ongoing commitment to purity, quality and reliability have earned the trust of a growing clientele, including the world’s leading functional food and beverage, dietary supplement, cosmetic and pet food manufacturers who have become loyal customers through the years.
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