Nicergoline is an ergoloid mesylate derivative used to enhance mental clarity, perception and concentration. Nicergoline, currently being used in the battle to treat senile dementia, has been found to improve mental agility through enhancing perception and vigilance. In this way it differs from the effects of Hydergine® (to which it is chemically similar) which improves oxygen stability and increases mental ability.
Nicergoline has alpha-adrenolytic action which activates the brain’s metabolism and improves arterial flow, lowers vascular resistance and improves the use of glucose and oxygen. Furthermore, it is known that Nicergoline inhibits platelet aggregation, and, animal experiments have shown, it increases nerve growth in the aged brain.